What is a Non-invasive Prenatal Paternity Test?

July 23, 2024by Adam Sacks

Determining paternity during pregnancy carries legal, social, and medical benefits. Establishing paternity allows for legal rights and responsibilities to be determined accurately. This ensures the father’s involvement in important decisions regarding the child’s welfare, including custody, visitation, and allows for financial support for the child.

 

Non-Invasive Prenatal Paternity Testing

Non-invasive prenatal paternity testing is a method used to determine the biological father of an unborn child without posing any risk to the fetus or the mother. This innovative procedure relies on the presence of free-floating fetal DNA in the mother’s plasma, which can be extracted and analyzed. By comparing the DNA profile of the alleged father with that of the fetus, paternity can be established with a high level of accuracy.

The process of non-invasive prenatal paternity testing involves obtaining a blood sample from the mother and a saliva or blood sample from the alleged father. The mother’s blood sample is then processed to extract the fetal DNA, which is present in a small proportion. The fetal DNA is then separated and analyzed for genetic markers that are unique to the alleged father.

What makes this test non-invasive is the fact that it does not involve collecting amniotic fluid or any invasive procedures, such as amniocentesis or chorionic villus sampling. These invasive procedures carry a small risk of harming the fetus, making non-invasive prenatal paternity testing a safer alternative.

 

Non-Invasive Prenatal Paternity Testing

 

Limitations on Timing for Non-invasive Prenatal Paternity Test

The timing for a non-invasive prenatal paternity test is subject to certain limitations. This type of test can be performed once the mother is around 7 to 10 weeks pregnant. Prior to this timeframe, there may not be enough fetal DNA present in the mother’s bloodstream to accurately determine paternity. Therefore, waiting until the 7-10 week mark is essential for a reliable test result.

The accuracy of a non-invasive prenatal paternity test can be affected by several factors, one of which is the gestational age. As the pregnancy progresses, the quantity of fetal DNA in the mother’s bloodstream increases, making it easier to detect and analyze. Therefore, the test tends to be more accurate in later stages of pregnancy, such as during the second and third trimesters.

Another factor that can impact the accuracy of the test is the quantity of fetal DNA present in the mother’s bloodstream. This can vary between mothers, and in some cases, the amount may be insufficient for an accurate result. If the test is performed too early or if the fetal DNA concentration is low, there is a higher risk of obtaining inconclusive or inaccurate results.

 

Accuracy of Non-invasive Prenatal Paternity Testing

Non-invasive prenatal paternity testing has a high accuracy rate, with studies and statistics supporting its reliability.

One study compared non-invasive prenatal paternity testing with traditional invasive methods, such as amniocentesis and chorionic villus sampling. The study found that non-invasive prenatal paternity testing had an accuracy rate of over 99%, comparable to the invasive methods. This indicates that non-invasive testing is a reliable alternative to invasive procedures. Another study demonstrated that the non-invasive method had a sensitivity of 99.5% and a specificity of 100%, suggesting its high accuracy. [1]

The non-invasive prenatal paternity testing does have some limitations. Potential errors can occur due  contamination of maternal blood samples or genetic variations in the fetal and maternal DNA. False negative or false positive results can occur in rare cases.

If you are interested in establishing paternity with a paternity action, the experienced family law attorneys at Sacks & Sacks can guide you through the process and help you understand your options for non-invasive prenatal paternity testing. Contact Sacks & Sacks today to schedule a free consultation.

 

Accuracy of Non-invasive Prenatal Paternity Testing

 

FAQs

Q. Is the non-invasive prenatal paternity test safe?

Yes, the Non-Invasive Prenatal Paternity Test is completely safe. Unlike invasive methods such as amniocentesis or chorionic villus sampling (CVS), which carry risks of miscarriage, the NIPP test only requires a blood sample from the mother, posing no risk to the fetus​ [2]

Q. How accurate is the Non-Invasive Prenatal Paternity Test?

The Non-Invasive Prenatal Paternity Test is highly accurate, with results showing over 99.9% probability of paternity when the tested man is the biological father. The test’s accuracy is ensured by the advanced DNA analysis techniques used in the laboratory. [2]

Q. Can the Non-Invasive Prenatal Paternity Test be performed if the mother is expecting twins?

No, the NIPP test cannot be performed if the mother is pregnant with twins or multiples. This is because the test cannot accurately distinguish between the DNA of the two fetuses in the mother’s bloodstream. [3]

 

Sources:

[1] Taylor-Phillips, S., Freeman, K., Geppert, J., Agbebiyi, A., Uthman, O. A., Madan, J., Clarke, A., Quenby, S., & Clarke, A. (2016). Accuracy of non-invasive prenatal testing using cell-free DNA for detection of Down, Edwards and Patau syndromes: a systematic review and meta-analysis. BMJ Open, 6(1), e010002. https://doi.org/10.1136/bmjopen-2015-010002

[2] Non-Invasive Prenatal Paternity Test (NIPP). (2020, May 3). American Pregnancy Association. https://americanpregnancy.org/paternity-tests/non-invasive-prenatal-paternity-test/

[3] Non-Invasive Prenatal DNA Paternity Testing – Asure Test, Inc. (n.d.). Www.asuretest.com. Retrieved July 8, 2024, from http://www.asuretest.com/services/dna/prenatal.php

by Adam Sacks

Adam Sacks is lead Family Law Attorney at Law Offices of Sacks & Sacks, P.A. in Jacksonville, Florida. He has a BA in Psychology from 1994, and received his Juris Doctor Degree in 1999 from the Western Michigan University Cooley Law School.

Sacks and Sacks Law
1646 Emerson St. Suite B Jacksonville, FL 32207

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